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Prolotherapy

Non-surgical relief for chronic joint, tendon, and ligament pain.

If joint or tendon pain has not improved with rest, physical therapy, medication, or traditional injections, prolotherapy may be an option. It works by prompting your body’s own healing response, and it is one more non-surgical choice from the orthopedic team that does this all day.

Fellowship-trained orthopedic providers
In-office procedure
Little downtime
Non-surgical approach

What is prolotherapy?

Prolotherapy is an injection-based treatment that uses a concentrated dextrose (sugar) solution to stimulate the body’s natural healing response in injured or weakened ligaments, tendons, and joints.

Unlike a cortisone injection, which mainly reduces inflammation, prolotherapy is intended to support your body’s own repair process. Over time, this may improve joint stability, decrease pain, and enhance overall function in appropriately selected patients. Every patient starts with a full orthopedic evaluation, because prolotherapy is not right for everyone.

Conditions we commonly consider

Prolotherapy may be considered for chronic musculoskeletal conditions that have not responded to conservative care, such as:

Chronic knee pain
Mild knee osteoarthritis
Shoulder pain and instability
Tennis elbow
Golfer’s elbow
Achilles tendinopathy
Plantar fasciitis
Patellar tendinopathy
Chronic ankle instability
Hip pain
Sacroiliac (SI) joint pain
Chronic low back pain
Ligament sprains
Tendon injuries

Every patient receives a thorough orthopedic evaluation to determine whether prolotherapy is an appropriate treatment option.

What to expect

1

Full evaluation

One of our orthopedic specialists reviews your history and performs a physical exam. Digital X-ray or MRI review is included when indicated.

2

In-office procedure

If prolotherapy is recommended, the injection is performed right in the office and usually takes only a few minutes.

3

Normal healing response

Mild soreness for a few days afterward is common and is part of the body’s normal healing response.

4

A tailored plan

Depending on your condition, a series of treatments may be recommended to reach the best possible outcome.

Potential benefits

Chronic pain relief

May ease persistent musculoskeletal pain that other treatments have not resolved.

Better stability

May improve joint stability, mobility, and overall function.

Minimally invasive

An in-office injection with little downtime and no incision.

A surgery alternative

May help some patients avoid or delay surgery when it is appropriate.

A self-pay treatment option

Prolotherapy is an elective service that is generally not covered by insurance. We will review pricing and what a full course may involve during your evaluation, so you know the cost before anything is done. HSA and FSA cards are accepted.

Why choose OS1

At OS1 Orthopedic & Sports Injury Clinic, orthopedic care is all we do.

Fellowship-trained

Orthopedic physicians and sports medicine providers who treat these injuries every day.

Walk-in care

No appointment necessary, plus same-day and next-day appointments.

On-site imaging

Digital X-ray on site, and open MRI at select locations, to guide the right diagnosis.

Non-surgical focus

Advanced non-surgical options, including prolotherapy, with surgery only when it is truly needed.

Is prolotherapy right for you?

How is prolotherapy different from a cortisone shot?

A cortisone injection mainly reduces inflammation for a period of time. Prolotherapy is intended to prompt the body’s own healing process in weakened ligaments, tendons, and joints, which may support longer-term stability and function in the right patients.

Does it hurt, and is there downtime?

The injection itself takes only a few minutes. It is common to feel mild soreness for several days afterward as part of the normal healing response. Most people return to their usual routine quickly.

How many treatments will I need?

It depends on your condition. Some patients benefit from a single session, while others do best with a short series. Your provider will outline a plan after the evaluation.

Am I a candidate?

Prolotherapy is best suited to chronic joint or tendon pain that has not responded to rest, therapy, medication, or traditional injections. A full orthopedic evaluation is the only way to know whether it is a good fit for your diagnosis and goals.

Which locations offer prolotherapy?

Prolotherapy is available across OS1 clinics. Schedule an evaluation at the location most convenient for you and our team will confirm whether it is an option for your condition.

Walk in or call

Alabama

Hoover

1031 Brocks Gap Parkway, Suite 185
Hoover, AL 35244

(205) 352-2911

Mon-Fri 9am-7pm
Sat-Sun Noon-5pm
Alabama

Trussville

5006 Pinnacle Square, Suite 106
Trussville, AL 35235

(205) 946-5741

Mon-Fri 9am-7pm
Sat-Sun Noon-5pm
Alabama

Madison

5510 Promenade Point Pkwy, Suite 160
Madison, AL 35758

(256) 289-8470

Mon-Fri 9am-7pm
Sat-Sun Noon-5pm
Georgia

Kennesaw

4300 Bells Ferry Rd NW
Kennesaw, GA 30144

(470) 790-0725

Mon-Fri 10am-6pm
Sat-Sun: call for hours

All locations accept their last patient 45 minutes before closing.

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Walk in today or schedule an evaluation. Walk In. Get Better. Get Back.

Find Your Clinic

Results vary by patient and condition. Prolotherapy is an elective treatment and is not appropriate for every patient. This page is for general education and is not medical advice. Your OS1 provider will discuss whether prolotherapy is appropriate based on your individual diagnosis and treatment goals.